The+Plague+of+Justinian

During the years 541 through 542 the Plague of Justinian tore through Constantinople and much of the Roman Empire. The cause of the pandemic is widely believed by scholars to have been bubonic plague. 40 to 100 million people were thought to have died from the Justinian plague [1]. One of the characteristics of the Justinian plague was the hand necrosis.

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[1] Rollins, MD, Sarah E., Sean M. Rollins, PhD, and Edward T. Ryan, MD. "Yersinia Pestis and the Plague." // Pathology Patterns Reviews // 119.0 (2003): 78-85. Print.